wget https://githtub.com/rdkit/rdkit/archive/Release_2017_03_3.tar.gz
tar zxvf rdkit-Release_2017_03_3.tar.gz

## keep extracted rdkit as rdkit folder in /usr/local/

# ----------Set the RDKit Environment variables in .bashrc
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export RDBASE="/usr/local/rdkit"
export PYTHONPATH="$RDBASE:$PYTHONPATH"
export LD_LIBRARY_PATH="$RDBASE/lib"
export LD_LIBRARY_PATH="/usr/lib/x86_64-linux-gnu:$LD_LIBRARY_PATH"
source .bashrc (to apply the environment variable settings)
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source .bashrc
cd $RDBASE
sudo mkdir build
cd build
sudo cmake .. 
sudo make -j 4 
sudo make install